{"product_id":"gm-csf-protein-rat","title":"GM-CSF Protein, Rat","description":"\u003ch4\u003eProduct Specification\u003c\/h4\u003e\u003cdiv class=\"responsive-table product-detail-table details-table\"\u003e \u003cbr\u003e\u003ctable style=\"width: 100%; height: auto;\"\u003e\u003ctbody\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSpecies\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eRat\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eGranulocyte-macrophage colony-stimulating factor, Colony-stimulating factor (CSF), GM-CSF\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAccession\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eP48750\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eAmino Acid Sequence\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eAla18-Lys144\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eExpression System\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eE.coli\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e\u003cp style=\"margin-bottom: 0px;\"\u003e14.5 kDa (Reducing)\u003c\/p\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e\u0026gt;95% by SDS-PAGE and HPLC.\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eEndotoxin\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e\u0026lt;0.1EU\/μg\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eConjugation\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eUnconjugated\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eTag\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eNo Tag\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003ePhysical Appearance\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003eLyophilized Powder\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStorage Buffer\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e20mM Tris,100mM NaCl, pH8.0\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e\u003cp style=\"margin-bottom: 0px;\"\u003eReconstitute at 0.1-1 mg\/ml according to the size in ultrapure water after rapid centrifugation.\u003c\/p\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eStability \u0026amp; Storage\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.\u003cbr\u003e · 3 months, -20 to -80℃ under sterile conditions after reconstitution.\u003cbr\u003e · 1 week, 2 to 8℃ under sterile conditions after reconstitution.\u003cbr\u003e · Please avoid repeated freeze-thaw cycles.\u003cbr\u003e \u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"width: 22%;\"\u003e\u003cstrong\u003eReference\u003c\/strong\u003e\u003c\/td\u003e \u003ctd style=\"width: 78%;\"\u003e\u003cp\u003e1.Cell Mol Immunol. 2021 Aug;18(8):2057-2058. Epub 2021 Jul 19.\u003cbr\u003e2.Biomaterials. 2021 May: 272:120786. Epub 2021 Mar 31.\u003c\/p\u003e\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e\u003c\/table\u003e \u003c\/div\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cdiv\u003e\u003cp\u003eGranulocyte-macrophage colony-stimulating factor (GM-CSF), which belongs to the colony-stimulating factor (CSF) superfamily and was originally identified as a hemopoietic growth factor, is mainly produced by lymphocytes and innate lymphoid cells. During inflammation, GM-CSF is principally produced by T helper (Th) cells and acts as a communication conduit between myeloid cells and tissue-invading lymphocytes. GM-CSF increased Treg numbers and its immunoregulatory activities that led directly to dopaminergic neuronal protection in the substantia nigra and striatum\u003c\/p\u003e\u003c\/div\u003e","brand":"UA BIOSCIENCE","offers":[{"title":"10μg","offer_id":46093708329133,"sku":null,"price":115.2,"currency_code":"USD","in_stock":true},{"title":"50μg","offer_id":46093708361901,"sku":null,"price":316.8,"currency_code":"USD","in_stock":true},{"title":"100μg","offer_id":46093708394669,"sku":null,"price":576.0,"currency_code":"USD","in_stock":true},{"title":"500μg","offer_id":46093708427437,"sku":null,"price":1281.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0751\/8493\/0989\/files\/AntBioImage_7ec1e04f-b92a-454a-81c2-34403446da18.png?v=1780945823","url":"https:\/\/norlato.com\/products\/gm-csf-protein-rat","provider":"norlato","version":"1.0","type":"link"}